Resveratrol supplementation

High-Dose Resveratrol Supplementation in Obese Men

Obesity, diabetes, hypertension, and hyperlipidemia constitute risk factors for morbidity and premature mortality. Based on animal and in vitro studies, resveratrol reverts these risk factors via stimulation of silent mating type information regulation 2 homolog 1 (SIRT1), but data in human subjects are scarce. The objective of this study was to examine the metabolic effects of high-dose resver...

The effects of one period interval training and resveratrol supplementation

Background: Interval exercises are a way to improve exercise performance. Oxidative stress caused by interval exercises and stress on the immune system is possible induced apoptosis change in indicators Bax and Bcl-2. Resveratrol may be effective in reducing apoptosis induced by interval exercises. The present study investigates the simultaneous use of resveratrol and interval exercises on apop...

Effects of Resveratrol Supplementation on Methotrexate Chemotherapy-Induced Bone Loss

Intensive cancer chemotherapy is known to cause bone defects, which currently lack treatments. This study investigated the effects of polyphenol resveratrol (RES) in preventing bone defects in rats caused by methotrexate (MTX), a commonly used antimetabolite in childhood oncology. Young rats received five daily MTX injections at 0.75 mg/kg/day. RES was orally gavaged daily for seven days prior ...

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The effect of aerobic exercise along with resveratrol supplementation on AMPK and MAFbx gene expression of myocardial diabetic rats

Background and Aim: Diabetes is a metabolic disease that is associated with heart injury. It has been shown that exercise training and resveratrol can improve the cardiac structure and function of diabetic subjects. The aim of the present study was to examine the effect of aerobic training along with resveratrol on gene expression of AMPK and MAFbx on cardiac tissue of diabetic experimental mod...